If you used the FNV 4GB Patcher to enable the use of more than 2GB of RAM, you will need to re-run it after re-installing files. The first solution is to use the 4GB Fallout New Vegas patch. After that, you launch the game from the 4gb mod instead of the traditional way. what i am saying is you must manually install. When installing New Vegas Script Extender (NVSE), the nvse_loader.exe file should be in the game root folder: i.e. Simple patcher to make Fallout New Vegas 4GB Aware. Problem being, I dont know how to get the ENB working when I run Fallout 4GB.
When using lots of big mods like textures, you may find that Fallout: New Vegas begins to struggle with its small allocation of virtual memory. Up next, you'll want to install the 4GB Patcher, then do the same with the xNVSE and drag the files within the folder to the 'Fallout: New Vegas' installation directory from your mod manager. ' steamappscommonFallout New Vegas'), so it's along with the FalloutNV.exe file. Mod manager don't put mods were the game's exe it it goes in the data folder(if i remember right).